Journal: The American Journal of Clinical Nutrition

Article Title: Delayed iron improves iron status without altering malaria risk in severe malarial anemia

doi: 10.1093/ajcn/nqaa004

Figure Lengend Snippet: Value of biomarkers or proportion by month and study group for all children who were randomly assigned to iron [all CM (n = 79), all SMA (n = 77), and CC who were iron-deficient at day 0 (n = 35)]. (A) Hemoglobin, (B) ZPP, (C) ferritin, (D) sTfR, (E) hepcidin, (F) CRP. Hemoglobin values are presented as the mean value at each time point; bars represent SD. Other biomarker values are the median value; bars represent IQR. Superscripts reflect significant differences (P < 0.05) at each time point as assessed by ANOVA for continuous outcomes, with Tukey's test for pairwise comparisons. All values aside from hemoglobin were log transformed before ANOVA. Differences in the proportion iron-deficient by ZPP (B) were determined by chi-square test. aDifference between SMA and CM; bdifference between SMA and CC; cdifference between CM and CC. CC, community children; CM, cerebral malaria; CRP, C-reactive protein; SMA, severe malarial anemia; sTfR, soluble transferrin receptor; ZPP, zinc protoporphyrin.

Article Snippet: Plasma concentrations of ferritin (Ramco Laboratories Inc.), soluble transferrin receptor (sTfR) (Ramco Laboratories Inc.), and hepcidin (Bachem Holding AG) were measured by ELISA at the University of Minnesota.

Techniques: Biomarker Assay, Transformation Assay

Journal: Lipids in Health and Disease

Article Title: Associations of dietary iron intake with cardiovascular disease risk and dyslipidemia among Chinese adults

doi: 10.1186/s12944-024-02058-4

Figure Lengend Snippet: Population characteristics by quintiles of dietary heme and non-heme iron intake

Article Snippet: The soluble transferrin receptor (TRFR) and transferrin (TRF) were determined via nephelometry (Siemens, Germany). ferritin (FER) levels were determined by radioimmunology (Bio-Tech, China).

Techniques:

Journal: International Journal of Molecular Sciences

Article Title: New Insights into Red Blood Cell Microcytosis upon mTOR Inhibitor Administration

doi: 10.3390/ijms22136802

Figure Lengend Snippet: Iron homeostasis parameters at the study time points. ( A ) Mean iron (Fe) concentration at the study time points. ( B ) Mean human soluble transferrin receptor (HsTfR) at the study time points, ( C ) Mean hepcidin concentration at the study time points. ( D ) Mean bone morphogenetic protein-6 (BMP-6) concentration at the study time points. * p < 0.05, ** p < 0.01 (paired t -test).

Article Snippet: The other parameters were determined using the ELISA method: human soluble transferrin receptor—hsTfR (EIA-4256, DRG International, Springfield, NJ, USA), hepcidin-Hepcidin-25 or H (EIA-5782, DRG International, Springfield, NJ, USA), interleukin-6—IL-6 (R&D, kit no D6050, R&D, Minneapolis, MN, USA), hemojuvelin—HJV (E-EL-HH0588, ElabScience, Wuhan, China), bone morphogenetic protein-6—BMP-6 (E-EL-HH1854, ElabScience, Wuhan, China).

Techniques: Concentration Assay